INHIBITION OF DEOXYRIBONUCLEIC ACID-DIRECTED RIBONUCLEIC ACID POLYMERASE IN ESCHERICHIA COLI AFTER INFECTION WITH BACTERIOPHAGE T4
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چکیده
منابع مشابه
Fidelity of in vitro transcription of T3 deoxyribonucleic acid by bacteriophage T3-induced ribonucleic acid polymerase and by Escherichia coli ribonucleic acid polymerase.
The fidelity of in vitro transcription of bacteriophage T3 DNA by T3 RNA polymerase and Escherichia coZi RNA POlymerase have been studied by DNA-RNA hybridizationcompetition studies with regard to (a) asymmetry of transcription and (b) the region of the T3 DNA transcribed by either polymerase. RNA transcribed by T3 RNA polymerase hybridized exclusively with the H strand of T3 DNA-the only stran...
متن کاملThe enzymatic methylation of ribonucleic acid and deoxyribonucleic acid. IX. Deoxyribonucleic acid methylase in bacteriophage-infected Escherichia coli.
Infection of Escherichia coli B with bacteriophages Tl, T2, or T4 results in increase in the activity of deoxyribonucleic acid methylase assayed in crude extracts of the infected cells. The largest increase is observed after infection with T2. phage; T4 and Tl phages lead to smaller increases in that order of decreasing magnitude. After infection with T3, T5, or T6 phages, a decrease in activit...
متن کاملChemical structure of a modification of the Escherichia coli ribonucleic acid polymerase alpha polypeptides induced by bacteriophage T4 infection.
The cr-polypeptides of Escherichia coli RNA polymerase are known to be chemically modified within 4 min after infection by bacteriophage Tq. This paper reports a crude system derived from T1-infected E. coli which will modify the cr-polypeptides of purified E. coli RNA polymerase in vitro. The product of this in vitro reaction is identical with the modified (Y found in viva ; it differs chemica...
متن کاملMiracil D: inhibition of deoxyribonucleic acid polymerase-deficient Escherichia coli.
Miracil D preferentially inhibited the growth of a deoxyribonucleic acid (DNA) polymerase-deficient Escherichia coli strain. This is taken to indicate that miracil D is capable of altering the DNA of living cells and that it may thereby be a potential mutagen and carcinogen.
متن کاملDeoxyribonucleic Acid Polymerase III of Escherichia coli
DNA polymerase III has been purified 4,500-fold from the Escherichia coli mutant, HMS83, which lacks DNA polymerases I and II. When subjected to disc gel electrophoresis, the most purified fraction exhibits a single major protein band from which enzymatic activity may be recovered. Polyacrylamide gel electrophoresis under denaturing conditions produces two protein bands with molecular weights o...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1964
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.51.4.553